Posts tagged pain
PAINAD Scale Can Help Caregivers Identify Pain in Loved Ones with Advanced Dementia
After watching Mom’s last days at the nursing home when she was uncommunicative, I often have wondered how caregivers would realize that a loved one who is at the end stages of Alzheimer’s was in pain. That’s where the Pain Assessment in Advanced Dementia (PAINAD) scale can be of use.
According to Lippincott’s Nursing Center.com, this scale is a behavior-observation tool for use with people who have More >
New device can reduce pain during colon cancer screening
Colonoscopy is regarded as the most thorough way to screen for colon cancer but the potentially life-saving procedure can also be painful. Scientists and engineers are continually researching new methods of screening to reduce patient discomfort while also ensuring the accuracy of the exam. Researchers at Tufts University’s School of Engineering led by Associate Professor of Mechanical Engineering Caroline G.L. Cao, Ph.D., have developed a device More >
New guideline on most effective treatments for diabetic nerve pain
The American Academy of Neurology has issued a new guideline on the most effective treatments for diabetic nerve pain, the burning or tingling pain in the hands and feet that affects millions of people with diabetes. The guideline is published in the April 11, 2011, online issue of Neurology®, the medical journal of the American Academy of Neurology, and will be presented April 11, 2011, at the American Academy of Neurology’s Annual Meeting in Honolulu. More >
Newer surgery for neck pain may be better
ScienceDaily (Apr. 11, 2011) A new surgery for cervical disc disease in the neck may restore range of motion and reduce repeat surgeries in some younger patients, according to a team of neurosurgeons from the University of California, San Francisco (UCSF) and several other medical centers that analyzed three large, randomized clinical trials comparing two different surgeries.
More than 200,000 Americans undergo surgery every year to alleviate More >
New guidelines on best treatments for diabetic nerve pain
ScienceDaily (Apr. 11, 2011) The American Academy of Neurology has issued a new guideline on the most effective treatments for diabetic nerve pain, the burning or tingling pain in the hands and feet that affects millions of people with diabetes.
The guideline is published in the April 11, 2011, online issue of Neurology®, the medical journal of the American Academy of Neurology, and will be presented April 11, 2011, at the American More >
AAN: Guideline Backs Pregabalin for Diabetic Nerve Pain
Action Points Explain that a guideline from the American Academy of Neurology recommends pregabalin for the treatment of diabetic nerve pain based on evidence of modest efficacy from four placebo controlled trials.
Note that several other anticonvulsants, some antidepressants, and transcutaneous electric nerve stimulation received a “probably effective” rating in the guideline.
HONOLULU — Among a variety of drugs and nonpharmacologic More >
Annals of Neurology publishes Diamyd Medical´s NP2 Enkephalin Phase I results in cancer pain
Diamyd Medical´s Phase I clinical trial results evaluating the safety and efficacy of the candidate drug NP2 Enkephalin to treat intractable cancer pain has been published in the medical journal Annals of Neurology.
The publication, entitled "Gene Therapy for Pain: Results of a Phase I Clinical Trial" details the results of Diamyd’s Phase I dose-escalation clinical trial of NP2 Enkephalin through the four month evaluation period. More >
Positive results from Neuros Medical Electrical Nerve Block technology study in chronic pain
Neuros Medical, Inc., a medical device company, announced promising results today from their recently completed feasibility study. The study was the first human test of the Company’s patented high frequency Electrical Nerve Block™ technology and focused on patients with chronic amputation pain which affects nearly one million patients in the U.S. During the study, four of the five patients reported their pain was reduced to zero.
Study More >
Headaches? Eczema? Tummy pain? They could all be caused by a common food allergy your doctor’s never heard of
Genny Masterman’s main memories of her childhood are of feeling constantly itchy, tired and bloated.
‘I had eczema on my legs, arms and all over my scalp ever since I was a little girl,’ says 35-year-old Genny.
‘It was not only desperately uncomfortable but looked terrible.
Genny Masterman suffered from eczema, bloating and gut pain. Three-and-a-half years ago, she discovered the More >
Headaches? Eczema? Tummy pain? They could all be caused by a common food allergy your doctor’s never heard of
Genny Masterman’s main memories of her childhood are of feeling constantly itchy, tired and bloated.
‘I had eczema on my legs, arms and all over my scalp ever since I was a little girl,’ says 35-year-old Genny.
‘It was not only desperately uncomfortable but looked terrible.
Genny Masterman suffered from eczema, bloating and gut pain. Three-and-a-half years ago, she discovered the More >
Avanir files IND for NUEDEXTA/AVP-923 Phase II clinical trial for central neuropathic pain in MS patients
Avanir Pharmaceuticals, Inc. (NASDAQ: AVNR) today announced that it has filed an Investigational New Drug (IND) application with the U.S. Food and Drug Administration (FDA) to begin a large Phase II clinical trial of AVP-923, an investigational drug for the treatment of central neuropathic pain in patients with multiple sclerosis (MS). The FDA has acknowledged receipt of the submission and the company expects that the IND filing will be subject to More >
Love Study: Brain Reacts To Heartbreak Same As Physical Pain
Love hurts, and that is not just a saying for the broken hearted. Heartbreak is a very strange distress. It is exquisitely painful, and yet we cannot find an injury on our body. New research finds that when you reminisce about the one that got away, the brain actually triggers sensations that you also feel in times of “real” physical pain, making heartbreak truly, physically painful to add to the emotional distress it sometimes causes.
HCG hormone therapy may benefit patients with intractable pain
Results from a small study of intractable pain patients being treated with the human chorionic gonadotropin (HCG) hormone reported that they had experienced pain free hours in the past month. These results were presented today at a poster session at the American Academy of Pain Medicine’s 27th Annual Meeting.
Forest Tennant M.D., Ph.D., of the Veract Intractable Pain Clinic in West Covina, California, presented the results. The study included More >
Weight loss improves knee pain from common arthritic condition, study says
ScienceDaily (Feb. 19, 2011) Knee pain related to osteoarthritis (OA) is a common complaint among obese individuals and retired professional athletes, especially former NFL players, but researchers presenting their work at the American Orthopaedic Society for Sports Medicine’s Specialty Day program on February 19th say they have a simple solution: lose weight.
"Our research on patients who were obese with early-onset knee osteoarthritis More >
Phase III study shows tapentadol ER relieves chronic pain associated with DPN
New research has been published indicating that patients suffering from a painful complication of diabetes may experience a significant improvement in their pain as measured by a pain intensity scale when using an investigational pain medication. This phase III study, which evaluates the safety and efficacy of tapentadol ER against placebo for relieving moderate to severe chronic pain associated with diabetic peripheral neuropathy (DPN), is published More >
Some Painkillers Increase Heart Attack Risk: Study
Non-steroidal anti-inflammatory drugs (NSAIDs) such as Advil and Celebrex can raise users’ risk of having a heart attack, a new study has found. This finding came after scientists looked at the results 31 trials involving the drugs. Researchers say their study’s results suggest that a patient’s cardiovascular risk needs to be considered before doctors prescribe the painkillers.
Source: http://www.healthcentral.com/heart-disease/news-564705-98.html
FDA Limits Acetaminophen in Prescription Pain Meds
Officials with the U.S. Food and Drug Administration (FDA) have announced that they will lower the maximum amount of acetaminophen permitted in narcotic painkillers such as Percocet and Vicodin. The FDA made this move because of reports of severe liver damage linked to acetaminophen in these combination drugs. Currently, combination opioid/acetaminophen painkillers can contain as much as 750 mg of acetaminophen, but over the next three years, the More >
Cadence launches OFIRMEV pain medication in the U.S.
Cadence Pharmaceuticals, Inc. (Nasdaq: CADX) today announced the launch of OFIRMEV™ (acetaminophen) injection, the first and only intravenous (IV) formulation of acetaminophen to be approved in the United States. The U.S. Food and Drug Administration (FDA) approved OFIRMEV in November 2010 for the management of mild to moderate pain, the management of moderate to severe pain with adjunctive opioid analgesics, and the reduction of fever. OFIRMEV More >
Diamyd commences NP2 Enkephalin Phase II trial to reduce cancer pain
“The serious unmet medical need of efficient pain relief is a strong driver for our team to continue development of NP2 Enkephalin and the NTDDS platform”
Diamyd has dosed the first subject in a Phase II clinical trial in the United States evaluating the ability of the candidate drug NP2 Enkephalin to reduce cancer pain.
Diamyd’s Phase II clinical trial with the candidate drug NP2 Enkephalin will recruit approximately 32 subjects More >
Smoking may worsen pain for cancer patients
ScienceDaily (Dec. 22, 2010) The relationship between smoking and cancer is well established. In a study published in the January 2011 issue of Pain, researchers report evidence to suggest that cancer patients who continue to smoke despite their diagnosis experience greater pain than nonsmokers. They found that for a wide range of cancer types and for cancers in stages I to IV, smoking was associated with increased pain severity and the extent More >
Spinal Botox injection reduces pain
Botulinum neurotoxin type A (BoNT/A)—better known as Botox—reduces responses to an inflammation-related pain stimulus when injected into the spinal canal in mice, reports a study in the January issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).
"BoNT/A, with its long-lasting antinociceptive effect, may be a useful analgesic in inflammatory pain," according to the new research, More >
Smoking leads to increased pain severity in cancer patients
The relationship between smoking and cancer is well established. In a study published in the January 2011 issue of PAIN, researchers report evidence to suggest that cancer patients who continue to smoke despite their diagnosis experience greater pain than nonsmokers. They found that for a wide range of cancer types and for cancers in stages I to IV, smoking was associated with increased pain severity and the extent to which pain interfered with a More >
Smoking can increase pain severity in cancer patients
The relationship between smoking and cancer is well established. In a study published in the January 2011 issue of PAIN, researchers report evidence to suggest that cancer patients who continue to smoke despite their diagnosis experience greater pain than nonsmokers. They found that for a wide range of cancer types and for cancers in stages I to IV, smoking was associated with increased pain severity and the extent to which pain interfered with a More >